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Skinceuticals Retinol 1 Maximum Strength Refining Night Cream, 1 Fluid Ounce

Perfect for problematic and photo-damaged skin, Retinol 1.0 contains 1% pure retinol, the highest concentration currently available, and should be used for advanced treatment of pre-conditioned skin. Designed for maximum efficacy and stability, SkinCeuticals Retinol is formulated with highest concentrations of pure retinol available and enhanced with the latest stabilization and delivery technologies. Our retinol products help stimulate cell regeneration and build collagen to diminish the appearance of fine lines, wrinkles, and age spots from both photo- and intrinsic- aging. Additionally, they help minimize the appearance of pore size, while correcting blemishes and blotchiness often associated with problematic skin.

Key features

  • Helps reduce appearance of fine lines, wrinkles, ages spots, blemishes, and blotchiness
  • Preserves optimal retinol stability and minimizes less erythema commonly associated with the use of retinol
  • Ensures maximum amount of retinol is delivered to the skin
  • Minimizes the appearance of pore size

Honest reviews


Awesome product!

I’m 45 years old and am using this product to combat sun damage. From what I understand, this is the strongest retinol product you can get without a prescription. In the beginning I used it nightly for about a week before I noticed light peeling. I’ve cut back to 2-3 times per week and am noticing a definite improvement in my skin. My skin feels so smooth to the touch now. A little goes a long way, and do be careful to avoid the creases around the nose….for some reason this area can get really raw and sore. I am also putting it on the backs of my hands and forearms as these areas are also showing signs of sun damage. The retinol is very drying to the skin so be sure to use a good moisturizer the following day. I will be coming back to update as I notice any changes to my skin, but so far so good!

Willa Oakland, ME

Good stuff!

I feel like this night cream has helped reduce fine lines that I was starting to develop. It does create a bit of a peeling (more of a flaking) effect a few days after beginning to use it. That effect has continued over the past month or so. I’m not sure if it will ever stop. I don’t use it every night. More like every other night after getting more used to it. Some spots are immune to peeling for me…like between my eyebrows. It does a great job of regenerating skin. I’ll continue to use this as part of my night time routine as I creep farther into my 30’s. Cure aqua gel is my favorite exfoliator to use following on this, since it’s very gentle and removes all of the flaking dead skin.

Dorothea Conesville, IA

A new container, finally!

This product WORKS! I purchased the 1.0 about 6 months ago and saw immediate results. I began using the cream 2x a week and increased it to 3 (sometimes 4) as I realized my skin was acclimating. It does cause dryness, so I avoid the eye area, corners of the mouth and neck.

Helga Church Road, VA


You don’t need prescription strength retinol if you can buy this one on Amazon. I’m so glad I gave it try because now I can get all my refills online 🙂

Nina Angeles, PR

If you’re looking for potency, here it is!

I’ve been on the search for anti-aging products that actually DO SOMETHING for years. I came across Skinceuticals through a beauty application on my phone. It was one of the highest, AFFORDABLE, rated products outside of drugstore brands. I started out with the .5% retinol and I HIGHLY recommend that you do the same. DON’T just start at 1%. You NEED to definitely work up to that. I only use this about 2 times a week right now because it’s still very new for my skin but it’s worth every penny. My laugh lines are no where near as bad as they were when I started with Skinceuticals. My forehead is not near as defined by the wrinkles. I will definitely buy again.

Edythe Puerto Real, PR

Not for Newbies

This is really strong stuff. I should have started out with the weaker 0.5 formula. I burned my skin with it but I still give it a five star rating because it is potent as it claims to be. It was my own fault for not building up to this formula. I then ordered the 0.5 and am doing fine on it. Even the weaker stuff is powerful. Anyone starting out on any retinal products should not jump to the higher strength formula like I did.

Madeleine Niles, IL

Skinceuticals Retinol

I have used Retinol several times in the past and it works. This product simply put-does not work. After complete usage, I have had no effects whatsoever! I have never seen any pealing, any skin changes, no redness (if you apply too much) or any other typical Retinol effects. I would not recommend this product and should have saved my money for the prescription.

Jenny Mica, WA

It’s not a counterfeit.

This is a brand that my dermatologist dispenses. It is really pure 1% retinol. Use it with care. I use it once a day with a break every three or four days. My neck seems to be a little better.

Abby Redfield, IA

So far I love it

I have been suing this product for about 3 weeks now. Started out very intense. My face peeled pretty severely for a day or so. I reduced my usage to once every-other day until my face grew accustomed. Now I use it once a day at night time. My skin is still peeling a little bit, but not severely… Which I guess is what it’s supposed to do. I have very oily skin which I think helps keep the flaking down.

Rosalinda Dana Point, CA

This is an excellent product

I love the skinceutical retinol. I have not tried any other that measures up to it. I use it on the body too. This is good stuff. Hard to find at a reasonable price. This was a bargain

Joan Houck, AZ

Great product.

Really will cause skin cell turnover. Was the perfect product to prep my skin for real Retin-A. I used it nightly and got results.

Rosemary Newbury Park, CA


Its very good, I used it day and night to get the peeling going and it has, now I can back off and use it every night. I can’t believe I waged this long to buy this stuff!

Adeline West Brookfield, MA

Not as strong as I was expecting

I had absolutely no reaction to this at all. Definitely no peeling. This is a nice feeling cream, and makes a pleasant night cream. No complaints there. It’s not as strong as I was expecting though, based on other’s reviews. I guess we’re all individuals and respond differently, but others said they peeled but I had nowhere near that type of reaction to it and I have pretty sensitive skin. Or so I thought? But maybe those were first time users of Retinol, I don’t know. There is another brand I have been using for the last year or so that is a 2% Retinol, and I REALLY love it (and it’s only $26) but I thought if that one was so good, maybe one that is twice the price will be even better? I know 1.0 % is less than 2.0%, but my 2% never made me peel, so I thought maybe somehow this Skinceuticals was somehow better. Maybe it was a different/stronger version of Retinol? Nope… not better, just twice the price. I will use the rest of this up, but then I’m going back to my old cream. I just don’t see any reason to pay twice as much. Oh, I will also mention, in my quest (or shall we say greed) for the ultimate Retinol cream I also bought another brand that was labeled as "Retrinal 0.05% Cream" and again, it was no better than the one I was using before just more $. So the lesson I learned was, expensive price and high-brow names don’t necessarily make it better. I’m a results snob more than a brand snob.

Marilyn Bandana, KY