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Skinceuticals A.g.e. Interrupter Mature Skin Treatment, 1.7-Ounce

A.g.e. interrupter is specifically formulated to improve the creping, thinning appearance of mature skin caused by intrinsic or internal aging processes such as glycation which occurs when excess glucose molecules stick to collagen and elastin fibers, eventually binding them together and leading to the formation of advanced glycation end-products (a.g.e.). glycated collagen and elastin fibers lose the ability to function normally, and the body cannot break them down and replace them, which leads to severe wrinkling of the skin. a.g.e. interrupter is a unique treatment formulated with 4% blueberry extract, 30% proxylane™, and 0.2% phytosphingosine to help prevent the glycation process and correct severe signs of intrinsic aging in mature skin.

Key features

  • Helps reverse the erosion of elasticity and firmness caused by advanced glycation end-product (A.G.E.), preventing the rigidification of collagen and elastin fibers
  • Restores water and nutrients to the dermal epidermal junction
  • Helps protect the skin’s barrier to alleviate discomfort associated with dry, aging skin

Honest reviews


A face treatment that does what it says, but…

This expensive product made my skin look and feel very good for a couple of years. Over the past year I’ve noticed whiteheads, blackheads and bumps that I think are due to a build up of dead skin cells under the outer layer of skin. I read the ingredients more closely this time and among the ingredients listed are liquid wax. I am now wondering if that wax is what makes my skin look smooth. It doesn’t feel like it penetrates the skin. On my skinit may be blocking my pores and congesting my skin. I am using Skinceutical’s micro scrub gel and trying samples of firming face creams and serums for sensitive skin (currently firming cream from Body Time) to see if my skin improves.Another concern is that the cream contains aluminum something. I don’t want aluminum anything in my skin products. Some studies have suggested Aluminum plays a part in Alzheimers disease. I would not recomment this product because of this ingredient.This may not be a concern for many of you so I’ll check back in at this sight in a month to update my review.

Krista Rison, AR

Good Skin Treatment

I like it, but I not crazy about it. It light not grease, and soft my skin for me is an average cream, but good quality.

Rosalinda Hoquiam, WA

Net Picker

Skinceuticals A.g.e. Interrupter is just what it promises … a wonderful treatment for those of us who admit to having ‘mature’ skin. I have hypothryoidism, a condition that can cause many skin problems, especially dryness. The Skinceuticals A.g.e. Interrupter is the best moisturizer I have found in my quest for ‘normal’ skin. It is not greasy, and literally goes on like velvet. Almost immediately after application, makeup can be applied. I highly recommend this product.

Allene Sugar Grove, PA

Quality product + committed routine = healthy skin

I have been using SkinCeuticals A.G.E. Interrupter for about six years when recommended to me by my dermatologist. My skin is firmer, the pores smaller and generally an overall healthy glow; definite reduction of fine lines. The ingredients are a unique treatment formulated with 4% blueberry extract, 30% proxylane(tm), and 0.2% phytosphingosine to help prevent the glycation process that causes wrinkles to form.I use it on top of SkinCeuticals C E Ferulic in my morning routine.In the evening I use the CE Ferulic again withSkinceuticals Renew Overnight Dry Skin-refining Moisturizer For Normal Or Dry Skinon top.These products are pricey, but a little goes a long way. A bottle or jar will last me a good 9 months. I get compliments on my skin and have even been asked if I have ‘had any work done’. Nope; just these quality products, a committed routine, fresh air, drinking lots of water and not taking myself too seriously.

Hannah Mc Coll, SC

Magic Elixer

Really wonderful stuff. It’s thick so you don’t need much. Warm a small bit between your hands and lay it on lightly. Don’t forget your neck, and then rub any that’s left over your hands. You’ll be glad for this purchase. It turns back the hands of time and lasts as long!

Barbra Holyoke, MA

great product

I faithfully used this cream daily; moreover it is highly recommended by my dermatologist. I received positive comment about my face

Lois Atwater, CA

Fabulous Product

Have been using for several years and love it. I get a lot of complements on my skin and I attribute to this product.

Mollie Vandalia, OH


I use this product twice a day-AM & PM and love it. Very light and feels great on my skin.

Jenna Bassett, WI

Cream – yes; fragrance – no.

I have recently begun using this product. It is a good overnight cream that does not make my sensitive skin break out and seems to leave it well-hydrated in the morning.My problem is the fragrance – according to the company, the result of "natural" ingredients as opposed to fragrance additives. Nonetheless, it is a strong fragrance, much stronger than those in other natural or organic products that I use. I am not sure if I will continue to purchase this product, although I like the results – hence the 4 stars – because heavy fragrance gives me headaches.Sniff before you buy.

Raquel Menasha, WI