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Nioxin Cleanser, System 4

Aqua/Eau/Water, Tealauryl Sulfate, Sodium Laureth Sulfate, Cocamidopropyl Betaine, Cocamide Mea, Hydroxypropyltrimonium Honey, Sodium Lauryl Glucose Carboxylate, Lauryl Glucoside, Dimethicone Propyl Pgbetaine, Glycol Stearate, Peg150 Distearate, Polyquate

Key features

  • A daily volumizing cleanser
  • Gently removes residue and DHT from the scalp and hair to promote a healthy scalp environment
  • Provides nourishing vitamins, proteins and amino acids

Honest reviews



Would love to try but all shampoos have sulfates which are well known to strip color from dyed hair. What a shame because they insist some of their shampoos are good for color treated hair, not if they have sulfates.

Lillie Carbondale, KS

It works!

This formula definitely helps my husband with his receding hairline. Since he’s been using it a few years back his hairline hasn’t "stopped" receding but it has slowed significantly. And what’s more he has been able to stop using his dandruff shampoo.

Nina Williston, NC

Improves health of hair until…

I wanted to wait two weeks before posting a review. I’ve come to this conclusion. This shampoo is really nice. However, it’s not going to help your hair grow, it’s just not. I am re-ordering though because a shampoo has never made my hair look as shiny and healthy as this product has. It’s like I have someone else’s beautiful hair on my head. An enormous improvement in hair health. I like it a lot, just don’t expect it I help your hair grow -update jan 14 as of December this product has actually increased oil in my scalp and caused my hair to become extremely dry. It just stopped working?

Ginger Enumclaw, WA

This stuff is overrated, overpriced, and worthless

I have been using this product for 6 months now and I see NO improvement whatsoever. In fact, my hair (the density of the hair strands) is WORSE! This shampoo makes my hair feel super-thin, flat and lifeless. I have also been using Nioxin Recharging Complex (the vitamins) and taking them daily and still no improvement.I will not be buying anything by Nioxin again. Why pay overpriced prices for lousy results?

Taylor Hazard, NE

Goodness, It Tingles!

But in a good way, totally.I was originally turned onto the Nioxin system by my mother’s hairdresser when I went home for a visit. Considering I’ve got some seriously thinning patches along my hairline, I thought "what the heck?" and picked it up for a try.I am SO glad these come in big bottles, because I seriously adore this cleanser. I’ve been using it for the past three or so months and I *am* seeing regrowth. It’s slow, and fine, but it’s there. But more than that, I can’t even describe how amazing my scalp feels after I’ve washed and conditioned my hair with this stuff! The tingle isn’t harsh, the peppermint smell is divine and definitely wakes you up in the morning, and afterwards… my hair is SO SOFT, my head so refreshed and scalp all tingleriffic.Even my husband has converted to using this system (he uses System 6 because his hair is coarser) and he loves it. Definitely expensive, but in my view? Worth it.

Jean Unalakleet, AK

Love it!

I am a woman. I started losing hair in my mid-twenties. Tried everything, no real luck. Started using this and Rogain and now that I am 36 years of age…my hair is thick and the hair that I lost along my hairline is back. In fact, it came back right after I started using this and Rogain. I have to say I wouldn’t be a believer of this product had I not used it myself.

Claudine Pontotoc, MS

Been using for about a year or so.

I’m 40+ yrs, female with alarmingly thinning hair. I started using the Nioxin system after a friend recommended it.I started using this along with the conditioner and the supplements. I noticed my hair stopped shedding almost completely! Although I accredit that mostly to the supplements, which are now off the market, I continue to use the shampoo, conditioner and also the thermal bliss spray and extra hold hair spray. They work best for my hair overall.Nioxin does not test on animals, which is why I use it instead of the other stuff.

Beverly Rawlings, VA

FANTASTIC product!!

My hair is thinning due to a medication I’m currently on, & my husband’s thinning is hereditary. My BFF used this product, also due to a hereditary condition, so recommended it to us. We both LOVE LOVE LOVE it! And it works GOOD, over time. My girlfriend no longer has to use it, it worked so good for her, at least for awhile! WELL WORTH the money it costs, you can “feel” it working. We don’t use conditioner, our hair has more body without conditioner, but there is a conditioner available if you want it.

Suzanne Lakeside, CT

Good product!!

My hairdresser recommended this product years ago when it first became available. My hair has always been extremely fine and thin. What I notice the most with this product is that I stop losing so much hair. If I cease using it for a week or so, I begin to notice the difference. My hair starts showing up on the floor and in the shower again.For me, this product has been worth the price. I don’t use the rest of the Nioxin line as I have found so far that the shampoo is enough.

Beverley Jenkins, MN

Has completely changed my hair for the better after a few months…

I bought this based on a friend’s recommendation and the many positives reviews I read on here, but I have to admit I was a little skeptical about whether anything could stop my hair from thinning. I’ve been using this shampoo along with the Nioxin 4-conditioner for several months now and my hair has completely changed for the better. It’s like night and day. Before I got this, my hair was in horrible shape. Falling out like crazy, getting noticeably thin, dull, dried out, broken, flat, limp, coated, frizzy…it was a disaster. When I first started using the shampoo, I could tell it helped my hair look a little less thin because it left the hair cleaner than the other shampoos I’ve used. So I kept using the shampoo and sure enough, my hair stopped falling out. I can’t tell whether it’s regrowing or not, but my hair looks thicker than it was when I started, plus the condition is so much better. It’s shiny, full and looks so much healthier. The frizzies and broken ends are gone. I get compliments now instead of wanting to hide my hair under a hat. I’m not sure how it worked, but the difference is dramatic and I won’t be changing shampoos anytime soon. It might be a little drying for someone with very dry hair, but if that’s the case, try using it every other day or so. The minty scent is very refreshing too! The 33.8 ounce bottle is huge and worth every penny. Best purchase I’ve made in a long time.

Judi Beckville, TX

Stopped thinning hair

My doctor recommended this shampoo as I was experiencing hair loss. Hair loss has stopped and it leaves hair shiny.

Shauna Edmore, ND

I am not impressed!!!

I tried this shampoo and have to say that I saw none of the results promised. Afterwards, my hair actually seemed thinner and lifeless; even dry and brittle. I am done trying anything that Nioxin puts out. I also tried Nioxin Intensive Therapy Recharging Complex too and that made my hair worse; it actually caused more hair loss, breaking and brittleness. NO THANK YOU NIOXIN!!!

Constance Curtis Bay, MD

The Best!

I won’t go without this shampoo, adding to it the conditioner and scalp treatment, my hair now looks full at the scalp level, no more flat thin looking hair with my scalp showing! The other products that claim to grow hair must be used continually in order to keep hair looking full, (as per my stylist) but if I run out of this product or use other shampoos in between, my hair is still full and healthy looking. This is an amazing product with absolutely noticeable difference.

Melody White Lake, SD

love it

Been using Nioxin for over 25 years. love it and it does grow hair! My husband and my son use.

Lillie Cresskill, NJ

Keeps the scalp invogorated while cutting through excess sebum

I’m an older lady and have had issues with thinning hair, due in part to the sebum in my scalp thickening. I use Nioxin System 4, which actually breaks down the sebum and unclogs the pores in my scalp, which has helped me to regrow some of my hair. It feels tingly and works well, so I am very happy with it!

Haley Astatula, FL


Have been using this product for years and believes it does help. Usually I get from Amazon or Ulta Three. I ran out and noticed a little salon at Walmart carried so bought it there, SAME PRODUCT THE NUMBER FOUR CLEANSER. Well, different color (actually like no color), different scent, a paper label was slapped on the back rather than the info being printed on the bottle itself. I noticed it is NOW made in Mexico rather than the U.S. I still have part of the bottle left from the scalp therapy and that says made in US. INTERESTING.I will be getting my next bottle directly from Amazon or going to Ulta Three and seeing if that is made here or in Mexico and is the old color and scent I’m used to. They obviously changed the formula otherwise why is the color and scent and even texture different between these two bottles that are both CLEANSER NUMBER FOUR?

Rocio Wheatland, CA

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The product arrived quickly, and appears to be good. Very good price. I would probably purchase this again since I like Nioxin products.

Hannah Capay, CA