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Neutrogena Healthy Skin Anti-Wrinkle Anti-Blemish Treatment, Clear Skin Cream, 1 Ounce

Healthy Skin Anti-Wrinkle Anti-Blemish Cream is the only anti-aging treatment that combines the #1 wrinkle fighter with the #1 blemish fighter in one easy-to-use formula. Retinol, the purest form of Vitamin A, works deep within skin’s surface where wrinkles develop. Salicylic Acid, a proven acne-fighting ingredient, penetrates deep into pores to treat blemishes and help prevent future breakouts. This light, oil-free formula glides on easily and absorbs quickly with no greasy residue. Skin is clearer, softer and smoother. Fine lines and wrinkles are visibly reduced.

Key features

  • Reduces the appearance of fine lines and wrinkles
  • Salicylic acid acne treatment
  • Dermatologist recommended
  • Treats and help prevent blemishes

Honest reviews


Didn’t work for me

I have sensitive skin, that is dry/oily combination. I have trouble finding the right products for my skin. I really had high hopes for this. I need something to fight the little acne and pimples I do get, mostly my jaw line and chin and nose area; but this is not the product. The first day I used it I broke out bad, and I am still recovering from it. I had very large pimples form from using it. I now use Simple day cream and seem ok with it. But finding the right moisturizer is agonizing for my troubled skin.

Angela Red Oak, GA

Great product

just received it a few days ago, and I can tell definitely how this is a very powerful cream, I use it as several on here recommended with the neutrogena facewash against acne .today however approx. day 4 of usage, I noticed my skin feeling a bit dryer and itchy. So I will use the cream only every other day as recommended.But your skin will feel very good and I believe this is THE creme to use if you have middle age./adult acnelike myself. Tried several other productswill update in a few weeks, but so far definitely will recommendUpdate :All the neutrogena are very effective when it comes to anti wrinkle and acne fighting, only draw back if you are prone to have sensitive skin like me, be careful how much you apply, and how often you apply it, otherwise it will really dry your skin out and your skin becomes very itchy.So make sure to follow the directions, do only apply to the effected area, stay away from anywhere from the eye area, about 1 inch at least, and try it out first and use it every other day or so.Even as I keep my Neutrogena products on hand for emergencies,:) , for the day to day use you maybe want to check out the Lush products that are also on sale here on Amazon. Dream Creme, amazing moisturizer(also for people who have dry skin due to Caner treatments !!!!) , Vanishing creme, amazing moisturizer for acne prone skin, deminishes redness, acne scars, and Herbalism, an organic cleanser.

Leonor Rocky Mount, MO

Not great

i have better luck with my acne on my chin using oil tree foot balm on my face.. 🙁 i had high hopes for this given the reviews but i havent seen a lick of difference.. back to the drawing board..

Pearl Barbers Point, HI

Noticed a difference the 1st day! =D

I love this stuff! It has a pleasant smell & does it what it claims! I was depressed over how my skin was looking & with this & the Neutrogena, Anti-Wrinkle, Anti-Blemish Cleanser, I noticed a noticable difference the next day even my mom said that my skin was pretty & asked what I have been using! I have sensitive skin so I only use a pearl sized dab all over my face once every other day after cleansing with said cleanser. Most face creams clog my pores &/or leave my skin super shiny but this doesn’t! Being on a fixed income, I needed an affordable beauty product that combats wrinkles AND blemishes all in one & that does what it claims to do! THIS is that product!

Marisa Dwarf, KY

I Love This Product!

This has been my go-to face lotion for three years now. When I was 24, I was diagnosed with an endocrine disorder that caused me to develop mild to moderate acne (in my mid 20’s!), and it was pretty horrifying, considering I had never had problems with it before. I also have patches of dry skin that can develop into eczema in the winter time if I don’t moisturize. I found that heavier moisturizers such as Dove gave me acne, but using acne medication alone dried out my skin and caused more eczema. Enter Neutrogena’s Anti Wrinkle Anti Blemish lotion. I wash off my makeup and put on this lotion every night before bed, and my skin stays clear. It’s never greasy, and as long as I use it every day, I rarely get a blemish. Another thing it helps is to fade dark spots. I had some mild hyperpigmentation on my neck and chin from prior acne, and this product significantly faded it. I tried switching to the other Neutrogena lotions (considering I am now 27, I thought I could go without the acne treatment), and, while my skin felt great, I still had a blemish pop up a few days after switching. Thus, I am back to old faithful and still loving it. I get compliments on my skin all the time. Neutrogena, I love your products!

Yolanda Bellows Falls, VT


Will buy again it feels great on skin and really helps with break outs agent seen much anti aging but I haven’t used too long yet but highly recommend its light but still moisturizing perfect for me in summer

Lynda Riverside, PA

Love it

First it smells amazing. Makes my skin so soft. I have not had any break outs or skin issues. Can use morning or night and has not dried my skin out.

Bianca S Coffeyville, OK

bang for your buck

this is an anti wrinkle cream with retinol that is the only proven method of helping to prevent wrinkles… other claims are more of a miracle, but I do feel as though retinol did help when I first starting seeing these lines under my eyes I immediatly bought retinol and it def stopped it from increasing and seemed to repair it. salyic acid works with retinol, unlike benzoyle peroxide that destroys the effects of retinol, Im 27, might as well start early in wrinkle prevention then start too late and keep my youthful face for as long as possible. This is totally non-greasy and feels the most natural compared to other lotion I havee tried from oil-free olay, and aveeno oil-free lotion as well… this just seems to work with the PH of your skin, so if its even muggy and humnid you dont feel… weighted down by lotion. I can also say that this product without the blemish treatment/night time is what helped with that wrinkle, so that is why I bought this one, seeing as I also have acne. Relatively speaking this is a good product in that you dont have to buy 2 seperate lotions, which will increase the amount you pay, and also you dont have to go through the hassel of putting 2 lotions on, which will save you time in early morning rush. It does go quick and you have to use more to feel covered then the night lotion of the similar line, but Im so happy with it, Im not going to stop buying it.

Manuela Elroy, WI

seems to work

i stop using Pro active,because its drying my face,and since im 38yrs old.. my skin starts to wrinkle.. and i hate it! absolutely hate wrinkles! but i wont get those botox thing! so i look for some products that would free me from zit,and would keep the wrinkles at bay..i went back using obagi.. but it doesnt work like it used to do..and i stumble on these! the name just covers my needs! ahhh! i thought maybe this is it!I have been using this for a month,and the first couple of days wasnt convincing,i still get alot of acne,get frustrated of course.. but i have been experimenting on different products on my face and see how one contradicts with the other,lets say if i use a l’oreal BB max as my sunblock,then id get zits right away,so i know that i should stop that now.. then i use the neutrogena anti wrinkle spf15 as my moisturizer and sunblock instead,i would still get small zits,which could be gone the next day because id sleep with this anti blemish anti wrinkle cream i guess ill just settle with’s my routine,wash face with the neutrogena anti wrinkle,Anti-blemish cleanser,for 60 seconds.. id repeat it,if i have sunblock on my face,i let it sit a couple more seconds,until the foam seems to be drying.. then i rinse it off..pat dry..then i followed it with celeteque acne solution,oil control toner,or the neutrogena alcohol free toner.. either one of them works well with me.. i have a sensitive skin btw..once it dries.. id linger for a couple of seconds for the product to be absorbed by my skin..then i follow it with this..neutrogena anti wrinkle,anti blemish treatment cream!i do this many time a day,and it doesnt dry my skin,i guess maybe because of the place where i live add to the moisture i get,its just so humid here in my country (PH) i recognize that by doing it every 8 hrs or less when im awake.. made the zit go away.. now my face is clearing up.. id get a zit still but it seems that the cream is controlling it..i ordered lots of these already,because like i say,im here in the PH.. we dont have these types of neutrogena products being sold here.i have not had a chance to visit my dermatologist yet,for other treatments that i used to have for my face.. like the vit.A peel,or spanish peel,or a derma roller treatment..but my face now looks great with these.. pores are smaller.. my face is tighter! really! its very tight.. well dont get me wrong about the tight thing.. its not like i cant smile anymore hahah! but its tight.. and my face is shinny tight! i love it as if i just had a spanish peel! without the red effect like you just had a little bit of tan of course!oh also.. once a week i would scrub my face with olay regenerist micro-dermabrasion,i do it,so my skin would peel a bit,and these creams would be absorbed better..once a week too id put Ole henriksen truth serum collagen booster.. its vit.c for the face.. and every 3 weeks,i would use the derma roller on my face,followed by any cream i use for the this time it would be this neutrogena cream!anyway! i love this for now.. will edit my review if there’s a different story.. but for now.. this product is just great!

Beverley Odell, OR

Overall good product

This product seems to have reduced my mind acne, I did experience slight redness during the first two weeks of using this. The minor irration began to lessen with the more I used it.

Ollie Phil Campbell, AL

Way cheaper on Amazon

Than I found it at Target or K-Mart (almost half the price in some cases). I’ve heard that the version of this without the benzyl peroxide is just as good because the pH level in this isn’t ideal, but I can’t vouch for that.

Mai Powder Springs, GA


I love this product. I have true combination skin and am over 40. This is the perfect product for it!

Lenore Arlington, VA


Really good moisturizer. Just a little bit of Retinol in it. Doesn’t cause me to breakout. Makes skin softer, clearer. Do not use if pregnant.

Brooke Pompeys Pillar, MT

Greasy and gross

Had no moisturizing and was just not a good product. It was really greasy and gross. I used it twice and have kept it in the drawer ever since. I would throw it away if it would not be wasteful. Not recommended at all.

Darla Emigrant, MT

Good stuff.

I’m getting old, and still have issues with break outs. Solves two problems in one tube! Price is ok considering retinol products are usually a little pricey.

Betsy Sandy Hook, KY